Gastric Cancer is cancer of the stomach. The most common variety, adenocarcinoma, is less frequent in the United States than seen in Japan and continental Asia. This may be because of the large amounts of smoked, salted and high-nitrosamine containing foods eaten in the Orient. Genetics and the stomach bacteria HP (Helicobacter pylori) may also play a role. Symptoms are often absent, but gastric cancer can present as anemia or as a non-healing ulcer. Here's one time that taking strong acid-blocking medicine without a diagnosis can get you in trouble—it can hide the pain associated with the cancer! Diagnosis is best made with upper endoscopy and biopsy, but repeated barium studies can also help. The treatment is usually surgical removal of all or part of the stomach and surrounding lymph nodes with chemotherapy radiation therapy (investigational).